Comparative Phytochemical and Antimicrobial Study of Ultrasound-Assisted Aqueous Extract from Fresh Plants of Bryophyllum pinnatum with Conventional Extraction Method
A F M Nazmus Sadat, Nusrat Zahan, Debobrata Sharma, Khairunnahar Smriti, FatemaTuz Zohora, Sanjida Halim, Mohammad Ali, Imranul Kabir, Sayeda Khadija Tuj Johora, Afroza Sultana
Citation
A F M Nazmus Sadat, Nusrat Zahan, Debobrata Sharma, Khairunnahar Smriti, Fatema Tuz Zohora, Sanjida Halim, Mohammad Ali, Imranul Kabir, Sayeda Khadija Tuj Johora, Afroza Sultana, “Comparative Phytochemical and Antimicrobial Study of Ultrasound-Assisted Aqueous Extract from Fresh Plants of Bryophyllum pinnatum with Conventional Extraction Method”, International Journal of Engineering and Applied Computer Science, vol. 04, no. 04, pp. 10-16, May. 2022.
Abstract
Bryophyllum pinnatum is a potential medicinal plant widely used in different tribes in Bangladesh. The leaves of B. pinnatum were used in the present study for the compatibility assessment of a proposed ultrasound-assisted green extraction method with the conventional extraction method. An aqueous Ultrasound-Assisted Extraction (UAE) by using both fresh and dried leaves of B. pinnatum was proposed in the present study and successively compared with the traditional methanolic and aqueous (decoction) extraction method. The promising extraction yield was found through the proposed extraction method which was much better than decoction and almost similar to the methanolic extraction method. Phytochemical contents were also observed similar to the methanolic extract. Both methanolic and UAE extracts obtained from B. pinnatum leaves showed favorable antimicrobial sensitivity against both grams positive (Staphylococcus aureus and Streptococcus pyogenes) and gram-negative (Escherichia coli and Salmonella typhi) bacteria. Extracts obtained from the decoction method showed slightly poor antimicrobial activities. The difference in efficiency and efficacy of aqueous UAE extract obtained from fresh and dried leaves was observed insignificant. This indicates there is no necessity to impart the drying stage before extraction normally practiced in the conventional extraction method. Drying of plant material is a common stage of the conventional extraction cycle which ultimately lengthy the process and impose cost due to energy consumption and labor. Ultrasound-assisted extraction may successfully decrease the overall extraction cycle and ultimately reduce the overall cost of extraction. This method also creates opportunities to replace the water instead of with hazardous organic solvent for phytochemical extraction.
h-index
6
i10-index
4
Impact Factor
2.35
A F M NAZMUS SADAT
Dr. A F M Nazmus Sadat is an Associate Professor in UODA, and Consultant of ISO, GMP, EHS, 5S, TQM, Kaizen, Bioequivalence Study, etc. (QHSE Solution BD). He is MS in Pharmaceutical Technology and B.Pharm (Hons.). He has completed his Ph.D. in Environmental Science from IES (RU).
NUSRAT ZAHAN
Ms. Most. Nusrat Zahan is Medical Affairs Servier for Bangladesh Operations. She has completed her B.Pharm (Hons.) and currently pursuing M.Pharm from UODA.
DEBOBRATA SHARMA
Mr. Debobrata Sharma has completed his B.Pharm (Hons.) and is currently pursuing M.Pharm from UODA.
KHAIRUNNAHAR SMRITI
Ms. Khairunnahar Smriti has completed her B.Pharm (Hons.) and is currently pursuing M.Pharm from UODA.
FATEMA TUZ ZOHORA
Ms. Fatema Tuz Zohora has completed her B.Pharm (Hons.) and is currently pursuing M.Pharm from UODA.
SANJIDA HALIM
Ms. Sanjida Halim has completed her B.Pharm (Hons.) and is currently pursuing M.Pharm from UODA.
MOHAMMAD ALI
Mr. Mohammad Ali is QA Executive at Eskayef Pharmaceuticals Ltd. He has completed his B.Pharm (Hons.) and is currently pursuing M.Pharm from UODA.
IMRANUL KABIR
Mr. Imranul Kabir is Senior Assistant Manager in QA at Eskayef Pharmaceuticals Ltd. He is currently pursuing B.Pharm (Hons.) from UAP.
SAYEDA KHADIJA TUJ JOHORA
Ms. Sayeda Khadija Tuj Johora is Senior Executive in R&D at Aristopharma Ltd. She is currently pursuing B.Pharm (Hons.) from UAP.
AFROZA SULTANA
Mrs. Afroza Sultana is a Lecturer in the Department of Pharmacy at KYAU. She has completed her M.Pharm and B.Pharm (Hons.) and currently she is a Ph.D. Fellow in the Department of Nutrition and Food Technology at JUST.
International Journal of Engineering and Applied Computer Science
EMPIRICAL RESEARCH PRESS LTD. LONDON UNITED KINGDOM
